Design Proteins with RFD4-Proteina Using Reward-Guided Inference-Time Search
Design Proteins with RFD4-Proteina Using Reward-Guided Inference-Time Search
The RFD4-Proteina can design octapeptide protein sequences, with over 2.5 billion combinations; 100-peptide sequences have possibilities exceeding the number of atoms in the observable universe, among which there are proteins that can be developed for new therapies; this model uses reward-guided reasoning to search for solutions to the protein design search problem.
Protein design is a search problem. Choose amino acids for an eight-residue protein sequence and more than 25 billion combinations are possible. Choose amino...
Protein design is a search problem. Choose amino acids for an eight-residue protein sequence and more than 25 billion combinations are possible. Choose amino acids for a 100-residue protein sequence and the number of possibilities exceeds the number of atoms in the observable universe. Somewhere in that space is a protein that opens a path to a new therapy. There are too many combinations to…
Source: NVIDIA Technical Blog · developer.nvidia.com