使用 RFD4-Proteina 通过奖励引导推理时搜索设计蛋白质
Design Proteins with RFD4-Proteina Using Reward-Guided Inference-Time Search
RFD4-Proteina 可设计八肽蛋白质序列，组合数超 25 亿种；100 肽序列可能性超可观测宇宙原子数，其中存在可开发新疗法的蛋白质；该模型通过奖励引导推理时搜索解决蛋白质设计这一搜索问题。
Protein design is a search problem. Choose amino acids for an eight-residue protein sequence and more than 25 billion combinations are possible. Choose amino...
Protein design is a search problem. Choose amino acids for an eight-residue protein sequence and more than 25 billion combinations are possible. Choose amino acids for a 100-residue protein sequence and the number of possibilities exceeds the number of atoms in the observable universe. Somewhere in that space is a protein that opens a path to a new therapy. There are too many combinations to…
来源: NVIDIA Technical Blog · developer.nvidia.com